MARH7 Polyclonal Antibody, 20ul Antibody Humanization Single nucleotide polymorphisms (SNPs) in

Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence

Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation

Mutations and alternative splicing in TSG101 occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression

Lacks transmembrane domains and is probably not involved in transport

which include cyclin A

MARH7 Polyclonal Antibody, 20ul Antibody Humanization Single nucleotide polymorphisms (SNPs) inMARCH7 is a member of the MARCH family of membrane bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004