Bcl-7a Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing Catalytic activity:Selective cleavage of Arg-|-Ile
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Bcl-7a Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing Catalytic activity:Selective cleavage of Arg-|-IleBCL7A (BCL tumor suppressor 7A) is directly involved, with Myc and IgH, in a three way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high grade B cell non Hodgkin lymphoma. The N terminal segment involved in the translocation includes the region that shares a strong sequence similarity
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