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Irregular spacing creates oscillating enzyme inhibition that reduces overall metabolic effect

The B12 serum level after injection has no bearing on the amount of B12 that reaches the tissue and, therefore, on the efficacy of the treatment

Cell lysates were pelleted by centrifugation at 30,000 g for 30 min and resuspended in Earles Balanced Salt Solution with Ca 2+ (pH 7.4)