SGCG Rabbit Polyclonal Antibody, 20ul Sampling Tubes a rare autosomal recessive disorder

a rare autosomal recessive disorder

Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed: 15314155

Many alternatively spliced transcript variants exist for this gene

They play important roles in intracellular vesicle transport and cell division (summary by Venturelli et al

The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells

SGCG Rabbit Polyclonal Antibody, 20ul Sampling Tubes a rare autosomal recessive disorderThis gene encodes gamma sarcoglycan one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin syntrophin alpha and beta dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset