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Mitochondrial dysfunction is associated with an upregulation of ROS production, which exacerbates oxidative stress, promotes neuroinflammation, and contributes to progressive neuronal degeneration in AD

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[7] Vitamin D toxicity presents chiefly as sustained hypercalcaemia with nausea, vomiting, muscle weakness, neurocognitive changes, or arrhythmias, progressing to nephrocalcinosis if untreated

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